We do have COVID-19 IgG/IgM Immunoassay rapid tests to fight the pandemic
0

Your Cart is Empty

Not a fluke! Schisto is linked to prematurity: lessons from a Philippine project

December 05, 2016

Not a fluke! Schisto is linked to prematurity: lessons from a Philippine project

In this short blog post we draw attention to schistosomiasis and its links to premature birth, in recognition of World Prematurity Day.

Researchers at Brown University in the United States are looking at schistosomiasis and its effects on pregnant women in Leyte, a community in the Philippines. As a quick reminder for those who have not been following our growing interest in this insidious fluke, schistosomiasis is a water-borne parasite that wreaks havoc on internal organs, depending upon its strain.

Schisto-h affects the reproductive organs, while schisto-j affects the liver and is perhaps the most insidious. Though the effects of schistosomiasis have been studied for years, intense examination of its health effects on mother and fetus during pregnancy have somehow been neglected in much research until recently.

Friedman and Kurtis and their team are finding a link between schisto-j, placental inflammation and adverse birth outcomes, including prematurity in the population in Leyte, Philippines. Mothers who have schistosomiasis-j have higher levels of endotoxemia (1.3 times in maternal blood, 2.4 times higher in the placenta). Endotoxins are in turn, associated with prematurity. The Brown team has found that in pregnancy, schisto-j eggs also have proinflammatory response, also associated with prematurity and other adverse pregnancy events including intrauterine growth restriction and low birthweight.

Put in layman's terms, the schistosomiasis eggs cause a chronic infection and a long-term inflammatory response which is linked to problems in the placenta as well as in the maternal bloodstream.

But how big a problem is it potentially? Schistosomiasis affects some 200 million people worlwide, 40 million women of reproductive age. Schisto-j is endemic in countries with huge populations: China, The Philippines and Indonesia. Suffice it to say, that the problem is large and further exploration of the troublesome fluke in all its forms is important for women's health and for the prevention of prematurity.

 


Leave a comment

Comments will be approved before showing up.


Also in The Maternova blog

High-Fidelity Lactation Simulators Hit the Market and Spur More Realistic Teaching on Breast Health and Lactation
High-Fidelity Lactation Simulators Hit the Market and Spur More Realistic Teaching on Breast Health and Lactation

January 03, 2021

Maternova is proud to partner with LiquidGoldConcept, a women-founded team of experts, who have created a high-fidelity lactation simulator capable of modeling a wide variety of breastfeeding complications. The world’s first realistic  and wearable  breastfeeding training tool for parents, students and medical providers, LiquidGoldConcept’s lactation simulation models simulate a wide range of normal (and abnormal) conditions that include early stage mastitis, engorgement, plugged ducts, as well as nipple damages and fissures.
Read More
2020 in Review: The State of Maternal and Neonatal Health
2020 in Review: The State of Maternal and Neonatal Health

November 04, 2020

Assessing the global status of maternal and neonatal health in 2020 presents a varied, albeit alarming, view of the lives of mothers and newborns around the world. The socioeconomic strain of the COVID-19 pandemic, moreover, has caused upticks in adult and child malnutrition, leading experts to predict a rise in maternal and neonatal mortality this year. 

Read More
New preeclampsia risk-factor checklists to aid health care providers in identifying pregnant women who may benefit from prophylactic low-dose aspirin
New preeclampsia risk-factor checklists to aid health care providers in identifying pregnant women who may benefit from prophylactic low-dose aspirin

August 14, 2020

This past June, the Society for Maternal-Fetal Medicine (SMFM) published in the   American Journal of Obstetrics and Gynecology   a special statement on a collection of two new checklists they created to support health care providers in identifying pregnant women at heightened risk of developing preeclampsia, a major cause of maternal and perinatal morbidity and mortality. 
Read More
News & Updates

Sign up to get the latest on sales, new releases and more …

maternal and newborn health news